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Research Hub

Lipids, Medications and Testing

Cholesterol science, ApoB, statins, PCSK9 inhibitors, and what to actually measure on your lab panel.

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Testosterone Therapy and Your Heart: Why Your Total Score is Misleading

Imagine a man named Mark. Mark is 48 years old, and lately, he feels like a shell of his former self. Every day around 3:00 PM, he hits a "wall" of exhaustion that feels like swimming through deep mud. His "brain fog" makes it hard to focus at work, and he has completely lost the "spark" for his hobbies and his relationships. He is tired, moody, and just wants to nap.

The Million-Dollar Molecule: Why Your Body Pays a Fortune for Cholesterol

If your body were a blockbuster movie, cholesterol would be the character everyone loves to hate. We usually hear about it as the "villain" of the story—the bad guy responsible for heart trouble and clogged pipes. But if cholesterol is so truly "bad," why is it found in every single cell of your body? Why does your body work so hard to keep it around?

Children With 60-Year-Old Arteries: The Extreme Reality of HoFH

Imagine your body is a car, and your health is tracked by an odometer. For most of us, that odometer ticks up slowly and steadily. We might drive for 50 or 60 years before the engine starts to show significant wear and tear. But for some children, the odometer is spinning wildly out of control from the moment they are born. This is the reality of Homozygous Familial Hypercholesterolemia, or HoFH.

The Heart Health App That Finally Asks the Right Question

There are hundreds of heart health apps on the market today. Most of them do the same thing: they monitor your heart rate, track your steps, measure your sleep, and tell you to eat more vegetables. Some of the more sophisticated ones connect to wearables and give you a real-time readout of your pulse. A few will even flag an irregular heartbeat.

The Big Cholesterol Lie: Uncovering the Diet Industry’s Organized Denial

Imagine a doctor sitting in a dark room, peering through a powerful microscope at a tiny blob of yellow fat. For almost a hundred years, doctors looked at these blobs and thought they had found the "bad guy" causing heart disease. They called it cholesterol, and they believed that simply having too much of this "yellow grease" in your blood was the reason pipes in the body got clogged.

Why Your ‘Normal’ Cholesterol is Actually a Warning Sign

For decades, we have been told that a "normal" cholesterol level is the golden ticket to a healthy heart. But modern science has revealed a startling truth: what we once called "normal" was never actually healthy. In the 1960s, a total cholesterol level of 240 mg/dL was considered a standard, acceptable baseline for an adult. Today, a doctor would view that same number as an urgent health crisis.

The Heart Test Your Doctor Isn’t Ordering

A Coronary Artery Calcium (CAC) scan is a quick, painless CT scan — no dye required — that measures the amount of calcified, hardened plaque in the arteries around your heart. The result is your CAC score.
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