The Cholesterol Breakthrough: From Daily Pills to Twice-a-Year Shots

Atherosclerotic cardiovascular disease (ASCVD) remains the leading global cause of mortality despite major advances in acute care. Modern preventive cardiology increasingly recognizes apolipoprotein B (ApoB)–containing lipoproteins as the necessary and causal drivers of atherosclerosis.
Power of Zero: No Calcium – No Risk?

The clinical assessment of coronary artery calcium (CAC) has undergone a paradigm shift over the past three decades, evolving from a research tool to a central instrument in cardiovascular risk stratification.
Coronary Calcium and Athletic Risk

The landscape of preventive cardiology has undergone a profound transformation with the emergence of subclinical imaging, specifically the quantification of coronary artery calcium (CAC). For decades, cardiovascular risk assessment relied almost exclusively on probabilistic models derived from population-wide observational data.
Do Babies Need Statins?

For decades, the public has viewed heart disease as a “late-life accident”—a sudden collision of age and lifestyle that strikes in the golden years.
The Genetic Lottery: Why You Can’t Count on Being “Bulletproof”

We all know the story. It’s the legend of “Uncle Joe” (or Aunt Sally, or a neighbor down the street). He smoked a pack of cigarettes a day, ate bacon and eggs for breakfast every morning, never exercised a day in his life, and yet lived to be 98 years old with the heart of a teenager.