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Heart Disease and Fish Oil

Heart Disease and The Fish-Oil Confusion, the Vascepa Controversy, and What the Evidence Actually Shows For decades, cardiovascular medicine has been dominated by a single, ...

LDL “BAD” Cholesterol: Apolipoprotein B, Imaging Resolution, and the Illusion of “Normal” Coronary Arteries at Age 60

Apolipoprotein B, Imaging Resolution, and the Illusion of “Normal” Coronary Arteries at Age 60. The clinical assertion that individuals maintaining markedly elevated levels of low-density ...

Cholesterol for Athletes: How to Lower LDL Without Losing Your Edge (A Practical Guide to Statins)

If you’re an endurance athlete, you’ve probably had this moment: your fitness is undeniable—resting heart rate is low, VO₂ is high, your training log looks ...

The Future of Heart Disease Management

Cardiovascular medicine is undergoing a substantive paradigm shift, moving from a predominantly reactive, symptom-driven model toward a preventive framework grounded in early detection and individualized ...

Cholesterol: How Low is Too Low?

Can LDL Be Too Low? What PCSK9 Inhibitors Mean for Brain Health PCSK9 inhibitors are among the most powerful cholesterol-lowering treatments available. They can lower ...

Integrative Dynamics of Apolipoprotein B, Lipoprotein(a), and C-Reactive Protein in Atherosclerotic Progression

How we think about cardiovascular risk has changed a lot. We used to focus on total cholesterol and later LDL cholesterol (LDL-C) as the main ...

Pathophysiological Determinants of Atherosclerotic Regression: The Criticality of Ultra-Low-Fat Whole-Food Plant-Based Nutritional Protocols

Introduction: Challenging the Paradigm of Permanent Progression The management of coronary artery disease (CAD) has traditionally been viewed through the lens of “risk management.” In ...

Peter Megdal on The Lynchpin Podcast

Listen to The Lynchpin Podcast with Nora ...

The Hour That Would Not End

The heat inside the velodrome rose like a living thing, swelling from seventy-five to eighty degrees Fahrenheit as the desert afternoon pressed against the curved ...

Inflammation, Lipoproteins, and the End of the LDL-Centric Era

For decades, preventive cardiology has been anchored by a single, powerful concept: the "lipid hypothesis." We operated under the assumption that cholesterol accumulation—specifically LDL-C—was the ...

VO₂ max: the deriminant of Health and Longevity?

It's the prestige metric on every fitness watch and a key benchmark for vitality. But does a high VO₂ max actually make you live longer? ...

Rethinking Heart Health: How Peter Megdal Turned a Diagnosis into a Mission for Change

Health transformations often begin with a wake-up call — and for Peter Megdal, that call came from his own heart. After receiving a diagnosis that ...

Heart Disease in Masters Athletes: How I Reversed My Artery Blockages and Set a World Record at 65

Can an elite athlete have heart disease? Short answer: yes. I’m a lifelong endurance cyclist—now 65 years old - with three national records and two ...

Nattokinase and Cardiovascular Plaque: What the Human Research Really Says

People want simple answers to complex problems. Atherosclerotic plaque—that fatty, inflammatory buildup inside artery walls—feels like something you should be able to “clean out” like ...

The Great Nutrition Debate: Evidence-Based Realities of Paleo/Keto/Caveman vs Whole food plant based diets for Longevity and Heart Disease

In a world of "biohacking" and rapid weight-loss trends, two dietary paradigms often clash: the Low-Fat Whole Food Plant-Based (WFPB) diet and the high-protein/high-fat Paleo/Ketogenic ...

Keto vs. Whole-Food Plant-Based: What’s the hard evidence for performance, insulin sensitivity, heart disease reversal, and longevity?

What do people on social media mean by “ketosis,” and does it automatically mean “healthier”? Ketosis simply means your blood ketones (often β-hydroxybutyrate, βHB) are ...

The Protein Debate

Dr. Loren Cordain vs. Dr. T. Colin Campbell Original context: Public nutrition debate from the mid-2000s reflecting two competing paradigms: evolutionary biology versus whole-diet epidemiology. ...

Treating heart disease with diet isn’t just a modern obsession – it’s a practice backed by millions of years of evolutionary history and the sharpest tools in modern science

To truly settle the long-running "cold war" between Dr. Loren Cordain’s Paleo camp and Dr. T. Colin Campbell’s plant-based paradigm, we have to look past ...

Expert Angiographic Evaluation of Coronary Artery Disease Regression: The Megdal Serial Angiogram (2014–2018)

Atherosclerosis is a chronic, progressive vascular condition traditionally managed by interventions aimed at slowing its advancement.1 The measurable reversal of this condition—defined as structural regression—is ...

Peter Megdal gets second at National Championships

We all aspire to be winners, but what does it truly mean to be a winner? It’s often defined as someone who places first in ...
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